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曹勝利的科研成果

1. Wang, Y.; Zhang, M.; Cao, S. L.*; Lin, H. H; Gao, M.; Li, Z. F. Synthesis of 1-substituted 4(1H)-quinazolinones under solvent-free condition. Synth. Commun.2011, doi:10.1080/00397911.2011.566407.

2. Cao, S. L.*; Zhao, J.; Zhang, N.; Wang, Y.; Jiang, Y. Y.; Feng, Y. P. Synthesis and crystal structures of 4-(3-nitropyridin-2-ylamino)phenol and 4-(3-aminopyridin-2-ylamino)phenol. J. Chem. Crystallogr.2011, 41, 1456-1460.

3. Cao, S. L.*; Wang, Y.; Zhu, L.; Liao, J.; Guo, Y. W.; Chen, L. L.; Liu, H. Q.; Xu, X. Synthesis and cytotoxic activity of N-((2-methyl-4(3H)-quinazolinon-6- yl)methyl)dithiocarbamates, Eur. J. Med. Chem. 2010, 45, 3850-3857.

4. Cao, S. L.*; Guo, Y. W.; Wang, X. B.; Zhang, M.; Feng, Y. P.; Jiang, Y. Y.; Wang, Y.; Gao, Q.; Ren, J. Synthesis and cytotoxicity screening of piperazine-1-carbodithioate derivatives of 2-substituted quinazolin-4(3H)-ones,Arch. Pharm. 2009, 342, 182-189.

5. Cao, S. L.*; Zhang, M.; Feng, Y. P.; Jiang, Y. Y.; Zhang, N. Synthesis of 3-aryl-4(3H)-quinazolinones from anthranilic acids and triethyl orthoformate, Synth. Commun.2008, 38, 2227-2236.

6. Cao, S. L.*; Feng, Y. P.; Zheng, X. L.; Jiang, Y. Y.; Zhang, M.; Wang, Y.; Xu, M. Synthesis of substituted-benzylamino- and heterocyclylmethylamino-carbodithioate derivatives of 4(3H)-quinazolinone and theircytotoxic activity, Arch. Pharm. 2006,339,250-254.

7. Cao, S. L.*, Feng, Y. P., Jiang, Y. Y., Liu, S. Y., Ding, G. Y., Li, R. T., Synthesis and in vitroantitumor activity of 4(3H)-quinazolinone derivatives with dithiocarbamate side chains,Bioorg. Med. Chem. Lett.2005, 15, 1915-1917.

8. Cao, S. L.*, Wan, R., Feng, Y. P., New synthesis of thymidylate synthase inhibitor Raltitrexed, Synth. Commun.2003, 33, 3519-3526. 1. 曹勝利,許興智,廖薊,王瑤,韓瑩,趙保麗,劉紅芹,陳琳琳,李小榮,4-喹唑啉酮-6-甲氨基二硫代甲酸酯及其藥用組合物和用途, 申請號:201010034364.3,申請日期:2010-1-20

2. 曹勝利, 4-喹唑啉酮衍生物及其在抗腫瘤藥物中的應用, 專利號ZL 200510053618.5,授權公告日:2008.11.19

3. 曹勝利, 抗癌藥雷替曲塞的合成工藝, 專利號ZL 02131091.2,授權公告日:2005. 08. 31

4.曹勝利,許興智,廖薊,韓瑩,王瑤,趙保麗,2,4-二氨基喹唑啉的哌嗪二硫代甲酸酯衍生物及其制備方法和抗腫瘤用途,申請號:201110257528.3 主持國家自然科學基金面上項目、北京市教委科技計劃重點項目、北京市自然科學基金項目及北京市優秀人才培養資助項目等。在Eur. J. Med. Chem.,Bioorg. Med. Chem. Lett.,Arch. Pharm.,Synth. Commun.等國內外學術刊物上發表論文70余篇,近年來申請發明專利4項。

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